Видео игрица решава научне проблеме

[Grizzly Adams]

Веома занимљиво...

In just three weeks, gamers deciphered the structure of a key protein in the development of AIDS that has stumped scientists for years. According to a study published Sunday in the journal Nature Structural & Molecular Biology, the findings could present a significant breakthrough for AIDS and HIV research.

Using an online game called Foldit, players were able to predict the structure of a protein called retroviral protease, an enzyme that plays a critical role in the way HIV multiplies. Unlocking the build of the protein could theoretically aid scientists in developing drugs that would stop protease from spreading.

“Following the failure of a wide range of attempts to solve the crystal structure of M-PMV retroviral protease by molecular replacement, we challenged players of the protein folding game Foldit to produce accurate models of the protein,” the study reads. “Remarkably, Foldit players were able to generate models of sufficient quality for successful molecular replacement and subsequent structure determination. The refined structure provides new insights for the design of antiretroviral drugs.”

Developed by researchers at the University of Washington, Foldit turns scientific problems into competitive games. Players were charged with using spatial and critical thinking skills to build 3D models of protease. Few of these players had any kind of background in biochemistry.

According to Fox, it took players a matter of days to come up with models that were solid enough for researchers to translate into scientific rendering of the protein.

“People have spatial reasoning skills, something computers are not yet good at,” Foldit’s lead designer Seth Cooper said in a statement. “Games provide a framework for bringing together the strengths of computers and humans.”

Foldit has not only made this breakthrough with AIDS research, but it has also aided in Cancer and Alzheimer’s research. For more, read the study in its entirety here.

http://www.pcmag.com/article2/0,2817,2393200,00.asp

[Andre Williams]

ајд преведи, за нас полуписмене

[Grizzly Adams]

Ево да препричам кратко - научници су годинама имали проблем да провале 3D структуру протеина "ретровирусна протеаза" који је веома важан за размножавање вируса HIV-а (та структура је битна зато што од ње зависи како протеин функционише, па када то знају онда научници могу да праве лекове који на њега делују). Онда су направили онлајн видео-игрицу у којој се играчи (који генерално немају појма о биохемији) такмиче ко ће направити бољи 3D модел протеина. И проблем решен за три дана, тј. три седмице...

[Juan Valdez]

Hahahah Moram ovo da pošaljem mentoru. Bezveze da plaća naučnu radnu snagu kad može samo da kupi igrice i da deci (maloj i velikoj) da se igraju.

[Andre Williams]

хвала.

размишљали су неоптерећени гомилом "непотребних информација" ...

[Grizzly Adams]

Само леп пример како различити таленти могу да се удруже и направе супер ствари. Неко је наравно требало да истражи проблем, припреми све те податке, направи програм, играчи су само имали пажљиво припремљену "слагалицу" да реше. Фора је у томе што компјутери нису добри за решавање таквих проблема, а има људи са талентом за те ствари.

У сваком случају екипи која се досетила како да искористи све то - 1000000001010

[Милан М.]

"Games like World of Warcraft give players the means to save worlds, and incentive to learn the habits of heroes. What if we could harness this gamer power to solve real-world problems? Jane McGonigal says we can, and explains how."

http://www.ted.com/t...tter_world.html

Може доле да се изабере и превод, за оне који не знају енглески.

[Иван ♪♫]

ha, baš zanimljivo

[Milan Stanojevic]

Bas sam hteo da pomenem tu inicijativu na TEDu - zanimljiva je cela prica.